Globally, 62% of strokes and 49% of coronary heart disease are attributable to hypertension, a substantial disease burden4
About 20% to 30% of patients may have resistant hypertension—blood pressure controlled by with the use of more than 3 medications5
Patients with resistant hypertension are almost 50% more likely to experience an adverse cardiovascular event compared with patients with blood pressure controlled by 3 or fewer antihypertensive agents6